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Optimizing folate delivery with Metafolin® (L-5-MTHF)

An extensive body of evidence indicates that adequate folate intake may provide significant cardiovascular, cellular and neural protection. However, genetic variations affecting activation and metabolism of supplemental folic acid are highly prevalent. In line with our commitment to consistently offer innovative, science-based ingredients, Pure Encapsulations has updated a number of products†, including our multivitamins, to provide Metafolin® (L-5-MTHF).

Metafolin® is a naturally occurring, universally metabolized and active form of folate, L-5-MTHF. As such, it can be directly used in a diverse array of essential methylation reactions to support cardiovascular, neural and emotional health. Additionally, clinical evidence indicates that the bioavailability of Metafolin® is superior to folic acid. In a double-blind, randomized, placebocontrolled intervention study of 144 women of child-bearing age, 5-MTHF supplementation resulted in a greater accumulation of 5-MTHF in red blood cells than equimolar doses of folic acid.

Pure Caps products that containMetafolin®.

The Pure Packs incorporating these formulas will also contain Metafolin®.

PRODUCT NAME	ORDER CODES	INDICATIONS
Nutrient 950®	MVF3, MVF1, MVF9	women 18 to menopause
Nutrient 950® without iron	MVC3, MVC1, MVC9	men and postmenopausal women
Nutrient 950® without copper and iron	MVM1, MVM9	men and postmenopausal women
Nutrient 950® without copper, iron and iodine	MVI	men and postmenopausal women
Nutrient 950® with NAC	MVN2, MVN1	immune defense and detoxification support*
Nutrient 950® with Vitamin K	MVCK1	bone health and arterial calcium metabolism*
Nutrient 280®	MCF	sensitive individuals and children ages 12 and up
UltraNutrient®	UVC3, UVC1, UVC9	cardiovascular and liver health*
Polyphenol Nutrients	PHN3, PHN1	cellular, heart, liver, skin, cognitive, macular health*
Multi t/d	MTD1, MTD6	two-per-day dosing for optimal compliance; macular support*
Men’s Nutrients	MEN3, MEN1	men over 40; prostate health and more*
Women’s Nutrients	WN3, WN1	women over 40; breast health, hot flashes and more*
Longevity Nutrients	LGN2, LGN1	men and women over 60; cognitive support and more*
Athletic Nutrients	ATN1	training and performance*
PureLean Nutrients	PLN1	healthy glucose and lipid metabolism*
B-Complex Plus	BCP1, BCP6	balanced B vitamin formula
B6 Complex	B6C1, B6C6	balanced B vitamin formula with enhanced B6
Homocysteine Factors	HO1, HO6	cardiovascular health*
B12 Folic	B12	nerve and cognitive function*
Breast Health Complete	BHC1	general breast health support and comfort*
Lipotropic Detox	LD1	healthy hepatic function and detoxification*
Lysine-C Plus	LLP1	oral immune function*
Vita-Essentials	VIE6	balanced vitamin formula